Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/316141225?client_source=feed&format=rss
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Sunday, June 30, 2013
Saturday, June 29, 2013
"Game Consoles" Are the Final Key to Digital Domination
Google might be building
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German court dismisses bid for full Eichmann files
BERLIN (AP) ? Germany's foreign intelligence agency can keep secret some of its records on Adolf Eichmann, the man known as the architect of the Nazi Holocaust, a court ruled Thursday.
The Federal Administrative Court ruled that the intelligence agency was within its rights to black out passages from the files sought by a journalist attempting to shed light on whether West German authorities knew in the 1950s where Eichmann had fled after World War II.
Thursday's ruling followed a decision last year in which the court said the Federal Intelligence Service had to release some files it had previously kept secret.
Israeli agents abducted Eichmann in Buenos Aires in 1960 and brought him to Jerusalem for trial. Eichmann, who helped organize the extermination of Europe's Jews as the head of the Gestapo's Jewish affairs office during the World War II, was found guilty of war crimes, sentenced to death and hanged in 1962.
The mass-circulation Bild daily, whose reporter sued for the files' full release, has reported that West German intelligence knew as early as 1952 that he was in Argentina.
In 2006, the CIA released documents showing that it wrote to its West German counterpart in 1958, saying it had information that Eichmann "is reported to have lived in Argentina under the alias 'Clemens' since 1952" ? both his correct whereabouts and only a slightly different alias, which was actually Ricardo Klement.
The German intelligence service said in an emailed reaction to the ruling that most of the files it holds on Eichmann are already public and only a small portion still needs to be blacked out. It said that the need to do so stems from laws on "protecting state security interests" and data protection laws.
A lawyer for Bild's publisher, Axel Springer, said after Thursday's ruling that it reserved the right to take the case to Germany's highest court. Christoph Partsch said in a statement that Germany's interests would be harmed by redacting the files, not by releasing them.
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Frank Jordans contributed to this report.
Source: http://news.yahoo.com/german-court-dismisses-bid-full-eichmann-files-020711168.html
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Factbox: Scenarios for immigration legislation
By Richard Cowan
WASHINGTON (Reuters) - The debate over how best to fix U.S. immigration laws has been raging for months in Washington after President Barack Obama made the issue a 2013 legislative priority.
Prospects of a bill being enacted this year also got a boost when Republican Party leaders looked at the results of last November's elections and saw that their failed presidential candidate, Mitt Romney, won less than 30 percent of the Hispanic-American vote.
Embracing comprehensive immigration reform would give more Hispanics reason to at least consider Republican candidates, the Republican National Committee concluded.
Despite all this, House Speaker John Boehner has said a comprehensive immigration measure passed by the Senate Thursday will not be considered in the Republican-dominated House.
Still, things could change. Here are some scenarios laying out what could happen next in the immigration debate:
THE CONFERENCE ROUTE
* The wide-ranging bill that passed the Democratic-held Senate on Thursday, by a 62-38 vote, gets temporarily set aside by the Republican-controlled House of Representatives.
* This summer or fall, the House debates one or more narrow immigration bills. The most likely would be one that tries to stop all illegal immigration over the U.S. border with Mexico.
Other possibilities are a bill that provides more visas for foreign high-tech workers or one that helps American farmers get more cheap labor from abroad. None of these bills puts 11 million illegal immigrants on a pathway to citizenship, as the Senate bill does.
* Once the Senate and House have passed their respective bills, the two chambers appoint negotiators to work out a compromise - one bill that could pass both houses. The negotiators are called conferees and they meet in conference to hammer out a deal.
* The deal they work out is sent to the House and Senate where each chamber votes to pass the same bill that then would go to Obama for signing into law.
* The danger - one that Republican and Democratic aides say is likely - is that the conference deadlocks over the pathway to citizenship and the whole process collapses.
THE PING PONG ROUTE
* The House simply takes up the Senate-passed bill. Boehner already has ruled out this possibility because the majority of his Republicans oppose the Senate bill.
But some Democrats still harbor hopes that so much pressure will be thrust on the House in coming weeks and months to pass a comprehensive bill, one with the pathway to citizenship, that it will be forced to act on the Senate bill.
Obama no doubt will try to whip up support, as will immigration advocacy groups who are planning high-profile demonstrations and other lobbying efforts.
* The House relents and takes up the Senate bill.
* But it likely would amend it and send it back to the Senate to pass in its latest form.
* This process could continue with different versions flying back and forth between the House and Senate, like a ping pong game.
* Again, the danger is that each side ultimately sticks to its guns and the whole process collapses.
* Conversely, at some point, Boehner tells his rank and file that he has done all he can do to moderate the Senate bill and for the good of the party and the country, it is time to cut a deal. Some Congress-watchers say this is dangerous territory for Boehner. He could end up backing an historic bill that passes with the support of most Democrats and only a minority of Republicans. And that, some speculate, could put Boehner's job in jeopardy.
THE FASTEST DEAD-END ROUTE
* The Senate passes a bill.
* The House passes a much different bill or does nothing.
* Everybody agrees the two sides cannot work out a compromise and each side blames the other for failure.
* Immigration becomes nothing more than a political fundraising tool in the run-up to the 2014 congressional elections and 2016 presidential elections.
This already has begun.
Republican Representative Steve King, a Tea Party favorite from Iowa, made a fundraising appeal on Thursday in which he tried to cash in on his opposition to the Senate bill.
Calling the proposed pathway to citizenship "amnesty," King wrote, "Show the Senate, House leaders, and amnesty activists we won't stand for it by helping me raise $50,000 by midnight on June 30."
THE 2014 ELECTION ROUTE
Democratic strategist are looking ahead to the 2014 congressional election as a possible fall-back position.
If House Republicans refuse to pass comprehensive immigration reform, Democrats could run on the issue next year.
Democrats would target Hispanic and young voters to drum up support, possibly winning back control of the House.
"We could then pass immigration reform in 2015," said a senior Democrat aide.
(Additional reporting by Thomas Ferraro; Editing by Fred Barbash, Mary Milliken and Bill Trott)
Source: http://news.yahoo.com/factbox-scenarios-immigration-legislation-220556664.html
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Rosneft Oil Company: Rosneft agrees cooperation with Ministry of Internal Affairs
Rosneft and the Russian Ministry of Internal Affairs have signed a Cooperation Agreement.
The Agreement aims to strengthen the cooperation between the parties, including the measures to reduce the crime rate in the regions where the Company operates, assist the Russian Ministry of Internal Affairs in its exercise of powers to identify, prevent, combat, disclose and investigate crimes in the fuel and energy sector.
The preparation of the draft Agreement included the establishment of inter-agency working groups and the development of plans for joint activities aimed at improving the effectiveness of measures to decriminalize the situation around the Companys facilities.
The launched cooperation has already resulted in the success of a number of arrangements followed by instituted criminal proceedings. A recent example is the prevention of theft at a Samaranefteproduct gasoline station, which has been carried out in cooperation with the local authorities of the Russian Ministry of Internal Affairs and the Federal Security Service of Russia in the Samara region.
Rosneft will continue to focus on strengthening the systematic cooperation with law enforcement authorities to ensure the respect for law and order in the regions where the Company operates.
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Source: http://www.rustocks.com/index.phtml/Pressreleases/0/1/33907
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BlueStacks announces GamePop Mini, the 'forever free' version of its Android-powered console
Access to hundreds of apps from well-known developers with no up-front hardware cost
In an effort to expand the audience of its upcoming GamePop gaming subscription service, BlueStacks is announcing today that it will offer a smaller "forever free" version of its GamePop console. Dubbed the "GamePop Mini", this smaller console will offer much the same experience as its larger counterpart, but will be free with a subscription to its gaming service whereas the original GamePop will jump up to $129 up-front once its pre-order period ends.
This "Mini" version of the GamePop console will work in the same way as the larger version, connecting to your TV via HDMI and pairing up with your smart phone as a controller. The GamePop subscription service will remain the same for either console, giving customers access to games from over 500 partners -- including some of the best-known developers such as HalfBrick and Glu -- for just $6.99 per month. BlueStacks says at this point the subscription will offer customers access to the equivalent of $200 in paid apps with the single subscription.
Pre-orders for the original GamePop will end on June 30th, along with its promotional pricing, which will then open up the market for GamePop Mini pre-orders on July 1st at that magical $0 up-front price. The GamePop Mini is expected to ship to consumers this Winter.
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Source: http://feedproxy.google.com/~r/androidcentral/~3/lKrUThs1EE0/story01.htm
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Anchor is like Facebook for the workplace, launches today on iOS and the web
We don't usually cover business software around these parts, but Anchor, a social networking app launching today on iOS, goes out of its way to look like a regular app. The brain child of a former GM of Flickr and ex-VP at AOL, it's sort of like Facebook, in that it allows coworkers to join groups, post status updates, upload photos (complete with filters) and like each other's activity. (In lieu of a thumbs up, you give someone a rock-on sign.) It also has built-in chat and contact cards, so in theory you could use it as a one-stop shop for communicating with coworkers instead of cobbling together various other apps.
You could even compare it to Yammer, the social network eventually bought by Microsoft, except Anchor's co-founders say the app is more about coworkers bonding with each other, than necessarily being productive. (Imagine that!) Again, it's available today for iOS (and the web too), with free lifetime membership if you get it before September 25th. It's also coming soon to Android and Google Glass, we're told. With no commitment you should give it a try -- the UI is extremely slick -- though we have to wonder if it's really that big a faux pas to friend your coworkers on Facebook. After all, who's afraid of the occasional like from Tim Stevens?
Source: iOS app, web version
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Immigration overhaul: Senate passes historic bill
WASHINGTON (AP) ? With a solemnity reserved for momentous occasions, the Senate passed historic legislation Thursday offering the priceless hope of citizenship to millions of immigrants living illegally in America's shadows. The bill also promises a military-style effort to secure the long-porous border with Mexico.
The bipartisan vote was 68-32 on a measure that sits atop President Barack Obama's second-term domestic agenda. Even so, the bill's prospects are highly uncertain in the Republican-controlled House, where conservatives generally oppose citizenship for immigrants living in the country unlawfully.
Spectators in galleries that overlook the Senate floor watched expectantly as senators voted one by one from their desks. Some onlookers erupted in chants of "Yes, we can" after Vice President Joe Biden announced the bill's passage.
After three weeks of debate, there was no doubt about the outcome. Fourteen Republicans joined all 52 Democrats and two independents to support the bill.
In a written statement, Obama coupled praise for the Senate's action with a plea for resolve by supporters as the House works on the issue. "Now is the time when opponents will try their hardest to pull this bipartisan effort apart so they can stop commonsense reform from becoming a reality. We cannot let that happen," said the president, who was traveling in Africa.
After the bill passed, he called Sen. Chuck Schumer, D-N.Y., a leading author of the bill, to offer congratulations.
In the final hours of debate, members of the so-called Gang of 8, the group that drafted the measure, frequently spoke in personal terms while extolling the bill's virtues, rebutting its critics ? and appealing to the House members who turn comes next.
"Do the right thing for America and for your party," said Sen. Bob Menendez, D-N.J., who said his mother emigrated to the United States from Cuba. "Find common ground. Lean away from the extremes. Opt for reason and govern with us."
Arizona Republican Sen. Jeff Flake said those seeking legal status after living in the United States illegally must "pass a background check, make good on any tax liability and pay a fee and a fine." There are other requirements before citizenship can be obtained, he noted.
He, too, spoke from personal experience, recalling time he spent as a youth working alongside family members and "undocumented migrant labor, largely from Mexico, who worked harder than we did under conditions much more difficult than we endured."
Since then, he said, "I have harbored a feeling of admiration and respect for those who have come to risk life and limb and sacrifice so much to provide a better life for themselves and their families."
The bill's opponents were unrelenting, if outnumbered.
"We will admit dramatically more people than we ever have in our country's history at a time when unemployment is high and the Congressional Budget Office has told us that average wages will go down for 12 years, that gross national product per capita will decline for 25-plus years, that unemployment will go up," said Sen. Jeff Sessions, R-Ala.
"The amnesty will occur, but the enforcement is not going to occur, and the policies for future immigration are not serving the national interest."
In the Senate, at least, the developments marked an end to years of gridlock on immigration. The shift began taking shape quickly after the 2012 presidential election, when numerous Republican leaders concluded the party must show a more welcoming face to Hispanic voters who had given Obama more than 70 percent of their support.
Even so, division among Republicans was evident as potential 2016 presidential contenders split. Sen. Marco Rubio of Florida was one of the Gang of 8, while Sens. Rand Paul of Kentucky and Ted Cruz of Texas were opposed to the bill.
The legislation's chief provisions includes numerous steps to prevent future illegal immigration ? some added in a late compromise that swelled Republican support for the bill ? and to check on the legal status of job applicants already living in the United States. At the same time, it offers a 13-year path to citizenship to as many as 11 million immigrants now living in the country unlawfully.
Under the deal brokered last week by Republican Sens. John Hoeven of North Dakota and Bob Corker of Tennessee and the Gang of 8, the measure requires 20,000 new Border Patrol agents, the completion of 700 miles of fencing and deployment of an array of high-tech devices along the U.S.-Mexico border.
Those living in the country illegally could gain legal status while the border security plan was being implemented, but would not be granted permanent resident green cards or citizenship.
A plan requiring businesses to check on the legal status of prospective employees would be phased in over four years.
Other provisions would expand the number of visas available for highly skilled workers relied upon by the technology industry. A separate program would be established for lower-skilled workers, and farm workers would be admitted under a temporary program. In addition, the system of legal immigration that has been in effect for decades would be changed, making family ties less of a factor and elevating the importance of education, job skills and relative youth.
With the details of the Senate bill well-known, House Speaker John Boehner said at a news conference the separate legislation the House considers will have majority support among Republicans. He also said he hopes the bill will be bipartisan, and he encouraged a group of four Democrats and three Republicans trying to forge a compromise to continue their efforts.
He offered no details on how a House bill could be both bipartisan and supported by more than half of his own rank and file, given that most of the bills that have moved through the House Judiciary Committee recently did so on party line votes over the protests of Democrats. None envisions legal status for immigrants now in the country illegally.
Boehner declined to say if there were circumstances under which he could support a pathway to citizenship, but he made clear that securing the border was a priority.
"People have to have confidence that the border is secure before anything else is really going to work. Otherwise, we repeat the mistakes of 1986," he said, referring to the last time Congress overhauled the immigration system.
Rep. Nancy Pelosi of California, the House Democratic leader, also said he favors a bipartisan approach. At the same time, she noted that Democratic principles for immigration include "secure our borders, protect our workers, unite families, a path to legalization and now citizenship for those" without legal status.
While the outcome of the Senate vote was not in doubt, supporters scrambled to maximize the vote and fell short of 70, a level they had talked of reaching. Schumer spoke with New Jersey Gov. Chris Christie on Wednesday night as he lobbied ? successfully ? for the vote of the state's Republican Sen. Jeff Chiesa, whom the governor appointed to his seat.
___
Associated Press writer Donna Cassata contributed to this report.
Source: http://news.yahoo.com/immigration-overhaul-senate-passes-historic-bill-204725955.html
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Friday, June 28, 2013
Angelina Jolie, Matthew Vaughn Eyeing '300' Sequel Star Jack O'Connell for Lead Roles
By Jeff Sneider
LOS ANGELES (TheWrap.com) - Angelina Jolie's "Unbroken" isn't the only movie that "300: Rise of an Empire" star Jack O'Connell is testing for, as he's also in contention for the young lead in Matthew Vaughn's "The Secret Service," TheWrap has learned.
While John Boyega ("Attack the Block") and Christian Cooke (Cemetery Junction") are also in the mix, O'Connell is considered the frontrunner for the coveted role, though "Unbroken" would take priority should Jolie offer him the part.
Vaughn is mounting an adaptation of Mark Millar and Dave Gibbons' popular Marvel comic, which will star Oscar winner Colin Firth as a veteran secret agent who leads a young prot?g? into the shadowy spy business. Millar has described "Secret Service" as "James Bond meets My Fair Lady."
O'Connell has already tested for the role of Firth's nephew and insiders close to the process tell TheWrap that it went well, though they caution that Vaughn hasn't made a final decision yet.
The director had been eyeing his "Kick-Ass" star Aaron Taylor-Johnson for the role but his casting is considered a long-shot.
Vaughn's Marv Films banner is financing "Secret Service" and handling development in England, where O'Connell has earned a strong fan base thanks to his turn on "Skins." He also starred in such British hits as "This Is England," "Eden Lake," "Harry Brown" and "Tower Block."
Jolie's "Unbroken" is based on the bestselling book by "Seabiscuit" author Laura Hillenbrand. O'Connell is one of three actors testing to play American track star Louis Zamperini, who lived an incredible life that included surviving a plane crash only to become a POW in a Japanese prison camp during WWII.
O'Connell's competition for "Unbroken" includes Dane DeHaan and Alexander Dreymon, though it's possible Jolie could go in another direction and widen her search. Universal is distributing "Unbroken," which was recently rewritten by the Coen brothers.
What's interesting about these two projects is that Jolie's partner, Brad Pitt, produced Vaughn's "Kick-Ass" and starred in the Vaughn-produced thriller "Snatch." It's still early in the casting process, but it's possible both Jolie and Vaughn could pursue O'Connell's fall slot.
20th Century Fox plans to release "The Secret Service" on November 14, 2014. Vaughn, who last directed "X-Men: First Class" for Fox, is producing and directing from a script he co-wrote with frequent collaborator Jane Goldman. Vaughn's "Kick-Ass 2" producers David Reid and Adam Bohling are expected to be involved in a producing capacity. Shooting is scheduled to start this August overseas.
O'Connell was originally set to star in WB/Alcon's "Beautiful Creatures," but a visa issue stemming from legal trouble prevented him from shooting the film in America. He was eventually replaced by Alden Ehrenreich.
Warner Bros. will release "300: Rise of an Empire" on March 7, 2014.
O'Connell is repped by Conway van Gelder Grant and CAA, which had no comment several weeks ago when TheWrap first inquired regarding his screen test.
Source: http://news.yahoo.com/angelina-jolie-matthew-vaughn-eyeing-300-sequel-star-004221791.html
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Obama jabs Russia, China on failure to extradite Snowden
By Jeff Mason and Mark Felsenthal
DAKAR (Reuters) - U.S. President Barack Obama said on Thursday he would not start "wheeling and dealing" with China and Russia over a U.S. request to extradite former American spy agency contractor Edward Snowden.
Obama, who appeared concerned that the case would overshadow a three-country tour of Africa that he began in Senegal, also dismissed suggestions that the United States might try to intercept Snowden if he were allowed to depart Moscow by air.
"No, I'm not going to be scrambling jets to get a 29-year-old hacker," he told a news conference in Dakar, a note of disdain in his voice. Snowden turned 30 last week.
Obama said regular legal channels should suffice to handle the U.S. request that Snowden, who left Hong Kong for Moscow, be returned. Obama said he had not yet spoken to China's President Xi Jinping or Russian President Vladimir Putin about the issue.
"I have not called President Xi personally or President Putin personally and the reason is ... number one, I shouldn't have to," Obama said sharply.
"Number two, we've got a whole lot of business that we do with China and Russia, and I'm not going to have one case of a suspect who we're trying to extradite suddenly being elevated to the point where I've got to start doing wheeling and dealing and trading on a whole host of other issues," he said.
Snowden fled the United States to Hong Kong in May, a few weeks before publication in the Guardian and Washington Post of details he provided about secret U.S. government surveillance programs, then flew to Moscow on Sunday. He had been expected to fly on to Havana on Monday but did not board the aircraft.
The American, who faces espionage charges in the United States and has asked Ecuador for political asylum, has not been seen since his arrival in Moscow. Russian officials said he remained in a transit area at Sheremetyevo airport.
CHINA, ECUADOR HIT BACK
Snowden's case has raised tensions between the United States and both China and Russia. On Thursday, Beijing accused Washington of hypocrisy on the issue of cyber security.
Obama's remarks seemed calibrated to exert pressure without leading to lasting damage in ties with either country.
Andy Smith, director of the University of New Hampshire Survey Center, said Obama was trying to play down the Snowden saga and minimize the impact on the United States.
"The more the administration can play it down, the more latitude they'll have in the diplomatic arena to work out a deal for him," he said.
Obama predicted there would be a made-for-TV movie about the ongoing saga, but indicated that damage to U.S. interests was largely limited to revelations from Snowden's initial leak.
"I continue to be concerned about the other documents that he may have," Obama said. "That's part of the reason why we'd like to have Mr. Snowden in custody."
Snowden's revelations of widespread snooping by the U.S. National Security Agency in China and Hong Kong have given Beijing considerable ammunition in an area that has been a major irritant between the countries.
China's defense ministry said the U.S. government surveillance program known as Prism "has revealed the concerned country's true face and hypocritical behavior". It did not name the country.
"This 'double standard' approach is not conducive to peace and security in cyber space," ministry spokesman Yang Yujun told reporters, according to state news agency Xinhua.
In Ecuador's capital Quito, the government said it was waiving preferential rights under a U.S. trade agreement to demonstrate its principled stand on Snowden's asylum request.
In a deliberately cheeky touch from the leftist government of President Rafael Correa, Ecuador also offered a multi-million donation for human rights training in the United States.
Ecuadorean officials added that the U.S. fugitive's case had not been processed because he had not yet reached any of its diplomatic missions.
"USEFUL" CONVERSATIONS
Obama said the United States expected all countries who were considering asylum requests for the former contractor to follow international law.
In Washington, the U.S. State Department warned of "grave difficulties" for U.S.-Ecuador relations if the Andean country were to grant Snowden asylum, but gave no specifics.
The White House said last week that Hong Kong's decision to let Snowden leave would hurt U.S.-China relations. Its rhetoric on Russia has been somewhat less harsh.
Obama acknowledged that the United States did not have an extradition treaty with Russia, but he said such a treaty was not necessary to resolve all of the issues involved.
He characterized conversations between Washington and Moscow as "useful" and said the United States would continue to press.
Putin has rejected U.S. calls to expel Snowden to the United States and said on Tuesday the fugitive should choose his destination and leave the airport as soon as possible. Ecuador has said it could take weeks to decide on his asylum request.
Washington is focused on how former Booz Allen Hamilton systems administrator Snowden gained access to National Security Agency secrets while working at a facility in Hawaii.
Obama said the leaks exposed "pretty significant vulnerabilities" at the NSA that had to be resolved.
In Baltimore, NSA Director Keith Alexander said the leaks had caused "significant and irreversible damage" and hurt the United States as well as its allies.
"I believe the irresponsible release of classified information will have a long-term detrimental impact on the intelligence community's ability to detect future attacks," Alexander told the AFCEA International Cyber Symposium.
"I worry there will be more leaks."
(Corrects seventh paragraph to show Snowden went to Hong Kong in May)
(Additional reporting by Brian Ellsworth and Alexandra Valencia in Quito, Lidia Kelly in Moscow, Sui-Lee Wee in Beijing, Deborah Charles in Baltimore and Steve Holland and Laura MacInnis in Washington; Writing by Jeff Mason; Editing by Mike Collett-White)
Source: http://news.yahoo.com/obama-jabs-russia-china-failure-extradite-snowden-142851006.html
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Over-Engineered Speaker Cables? Nope, Actual Speakers
Do you live in a bizarre, warped, Escher-style home that's made installing a booming sound system next to impossible? The Anakonda KAN200 might look like a well shielded audio cable, but it's actually a flexible speaker designed to squeeze into spots where traditional boxy speakers don't fit, but still require jam pumping.
Flexible enough to even be wrapped around a pole, the Anakonda KAN200 can be mounted to curved surfaces or other irregularly shaped architecture, and up to 32 of them can be daisy-chained together to cover large spaces.
At over six-and-a-half feet long the Anakonda speakers are aptly named since installation is probably like wrestling a large snake, and at $900 per section they're actually not outrageously priced as far as high-end home audio gear goes. But unlike a real snake, let's hope these are properly balanced so they don't hiss. [K-array via Gizmag]
Source: http://gizmodo.com/over-engineered-speaker-cables-nope-actual-speakers-612362215
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What Are The Different Roasts Of Coffee Beans
Finally, your website includes a blog that covers such topics as the top protein powders, teas and green coffee beans being a fitness and fat lose supplement, basics on weight reducers and weight-loss, and preparing for the body building competition. These impressive effects were presented in the 243rd National Meeting & Exposition of the American Chemical Society in San Diego. These assistance to remove unwanted toxins through the body to assist your bodily organs to function better.
If you are about the search for the best pure green coffee bean extract, do your research. Try this and have that slender body again. The sealed capsules contains every one from the ingredients needed, you have no have to grind or mix.
Next the beans can ferment for several days in water, an activity that dissolves remaining traces of fruit pulp along with the sticky coating that surrounds the beans. This is additionally the stage where roast character is overtaking the origin character. An espresso coffeemaker, is a perfect demonstration of said multi function machines.
There are sure lots of variants of roasting to choose from. It is encouraging to find out the quantity of Indianapolis area coffee shops which can be either roasting their own pinto beans or acquiring them from local roasters. At now, the golden beans, called pergamino, have to be hulled, which is done by machine.
However, could I do this, there is a certain a higher level understanding I (and now we) must have with regard to sustainable coffee and its ecological significance. where to buy pure green coffee bean. Still within their original state, green beans are weighed and placed into a coffee roasting machine. But none have shown the dramatic results on this new study.
Other reports have linked caffeine to weight loss and a reduced chance of metabolic syndrome. Shade grown/shade-grown pinto beans: traditional espresso beans that are shade grown (with a canopy of trees). Bjava Coffee and Tea, at 56th and Lafayette, is among the most recent coffee shops to begin roasting their beans on site.
Green Coffee Pure Bean Extract is really a revolutionary product which has taken the weight-loss industry by storm. The researchers identified chlorogenic acid which is present in unroasted coffee beans as the reason behind this fat loss phenomenon. Drop in a handful of beans, and stir them around.
Include it in in your taste or coffee, you'll feel lighter. Is there a coffee antioxidant? So what about coffee shops in the past, did they exist, did they survive?
About the Author:
He is known by the name of Tory Paquin. Kansas is where he's been living for years and he does not intend on changing it. He is a library assistant however he's constantly wanted his own business.
Running is what he does every week.Gwendolyn is what people call her however she does not like when individuals use her complete name. Filing is exactly what she does. Her husband and her reside in Puerto Rico however she will have to move one day or an additional. As a lady what she actually likes is modelling trains and she is trying to make it a career.
Source: http://www.articlesnatch.com/Article/What-Are-The-Different-Roasts-Of-Coffee-Beans/5172988
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FileMaker Go 12 (for iPad)
FileMaker Go, which originally began life as a very solid $30 iPad app, should now be considered must-have mobile database software among desktop FileMaker Pro?users. The database program's excellent design, multiple file layouts, integrated search, digital signature capture, and charting capabilities made it a compelling offer when it debuted, but FileMaker Go 12 ups the ante with enhanced multimedia capabilities, multitasking support, and best of all a new price: Free! A few niggles still linger?you still can't create new files and there's no true two-way synchronization?but FileMaker Go 12 is an iPad?database app that can keep you productive while on the go.
What's It All About?
FileMaker Go 12 is designed to do one thing: run FileMaker Pro 12 software (both the regular and advanced versions) on Apple's slate. You cannot, however, create new files using FileMaker Go; that's reserved for the Windows and Mac desktop software. That sting is a bit easier to deal with now that that FileMaker Go costs absolutely nothing to download.
FileMaker Go 12 looks and functions very much like its FileMaker 1.2 predecessor. By default, FileMaker Go displays a very basic two-column interface that contains the heading "Files on Device" in the left column, and "Remote Files and Hosts" in the right column. This setup remains the same regardless of whether you hold the iPad in vertical or horizontal alignment. The "Remote Files and Hosts" column lets you connect to a remote host, and lists recently used FileMaker Pro 12 files. When you open a single file or multiple files, an icon appears in the upper-left corner that displays the number of open windows. Tapping that icon lets you effortlessly navigate through the open windows using a finger swipe.
The FileMaker Go Experience
After transferring a FileMaker Pro 12 database table to the iPad using iTunes' File Sharing feature, I tapped the file, causing it to open in full screen mode. I was pleased to see that the layout hadn't been altered in the transfer, and that I could edit any of the fields. You can have multiple records (think of them as pages) within a single database table, which you can smoothly navigate between by moving the slider at the bottom of the screen, or by tapping the forward or backward arrows. An options icon resides in the upper-right portion of the screen which you can use to change the view ("Form," "List," and "Table"), activate/deactivate the toolbar, print to an Airplay-enabled printer (or use AirPrint), and tweak other settings. Tapping "Save/Send" and then "Database" lets you email, save, or save and open a file, while tapping "PDF" lets your e-mail, view, or save a print-ready file. You can also export data in one of several new file formats including Excel, CSV, TAB, and HTML?very useful.
At the bottom of the interface are three icons that give additional functionality. The first, located to the far left of the navigation slider, lets you select one of 40 themes, including several iPad-friendly designs. The second, located to the right of the navigation slider, lets you add a new set of records to a pre-existing database table, duplicate a database table, delete a database table, or delete found records. The icon to the far right lets you search by file name, omit records from a file, and sort by various criteria (age, amount in stock, item, and much more). In addition, you can now add audio or video that you recorded with your iPad to a container field with just a few button taps. In my time with FileMaker Go 12, I found that all of the options worked smoothly, but FileMaker cautions that there may be some calculation and script behavioral differences when porting files into its mobile app.
Chart Support and Synchronization
FileMaker Go 12 supports Charts created with the desktop FileMaker Pro 12. You can view, edit, and update chart bar, line, and pie charts, but you can't create them from scratch? within FileMaker Go.
The previous version of FileMaker Go let you transfer FileMaker Pro files from your desktop to your iPad using iTunes (or, alternately, by opening and saving an e-mailed file), but the changes weren't synchronized; you needed to use FileMaker Pro on the desktop to import data, which was annoying as it resulted in multiple entries. But if you had files stored on a hosted FileMaker server, any changes that you made using FileMaker Go were automatically saved to the original database file. Overall, the experience was less than ideal.
The situation has been (somewhat) addressed. The Charts feature introduced in FileMaker 12 "syncs" FileMaker Pro data within the chart itself; it isn't, however, a true sync between the local file and the remote file as the changes aren't immediately reflected within the server or desktop software (you must export the changes you've made back to the FileMaker Pro 12). It's a decent first step, but true synchronization would be marvelous.
Digital Signatures
FileMaker Go now lets you accept digital signatures, which will prove a vital offering for those that signing contracts, confirming the receipt of goods, conducting field surveys, and more. Accepting a signature is as simple as having someone John Hancock the "Receiving Signature" field (either with a finger or iPad-compatible stylus). You can then export the captured signature to FileMaker Pro 12 or upload it to a FileMaker Server database. FileMaker 12 now supports multi-tasking so that when you leave the app and then return to it, you'll pick up exactly where you left off.
FileMaker A-Go-Go!
FileMaker Go 12, despite some limitations, is a useful tool for businesspeople who want to access databases on the go, as it gives them the option of shedding a laptop or roaming free from a desktop PC. The ability to create new files and charts from scratch would be a huge benefit (as would true synchronization), but even without those features, FileMaker Go 12 is a more than worthy download for FileMaker Pro 12 and FileMaker Pro 12 Advanced users who need to quickly retrieve, or input, important data on the go.
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/W6IXUJAho3U/0,2817,2381220,00.asp
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Charles Pugh, Detroit City Council President, Stripped Of Title, Salary By Kevyn Orr
DETROIT -- State-appointed emergency manager Kevyn Orr has ordered his legal staff to prepare an order that will strip the pay and authority from AWOL Detroit City Council President Charles Pugh.
Pugh has been a no-show at recent council meetings and failed to acknowledge by a 5 p.m. Wednesday deadline that he would be returning to work, Orr spokesman Bill Nowling said.
Orr will review the completed order and could sign it Thursday, Nowling said.
Orr is operating under Michigan's emergency manager law. He can't fire Detroit elected leaders, but does control their pay and responsibilities. Pugh earns about $76,000 per year.
His request for a three- to four-week medical leave was denied earlier this week by Orr.
The City Council's powers have been reduced since Orr was hired in March to fix a budget deficit barreling toward $380 million and about $17 billion in city debt. He has control over all matters involving money.
The Associated Press left messages Wednesday seeking comment from Pugh, who also is the subject of a complaint the Detroit Public Schools received from the parent of a recent graduate.
The mother, whose name was not released by the district, came forward earlier this month with concerns involving the 41-year-old Pugh and a mentoring program at Douglass Academy for Young Men, according to district spokesman Steve Wasko.
The complaint involved cash and gifts the teenager received while part of the program.
"At the time, the school reached out to the parent who stated that she would prefer to handle the matter personally," Wasko said Wednesday in a statement. "The school has since contacted the parent again in writing seeking to resolve the concerns, and is awaiting a response."
The district will review the leadership mentoring program at Douglass Academy, he added.
Detroit area attorney Ivan Land said he represents the teen's mother and told The Detroit News that the gifts included a $350 cellphone and prom clothing. The teen also received $160 in cash from Pugh, Land said.
Pugh, a former TV anchor, resigned in 2009 from Detroit's Fox Network affiliate and a local radio station to run for council. He became council president after receiving the most votes in that year's general election.
"I have a mandate from the people of Detroit," Pugh said after the election. "The people say they trust me and believe in me, and are looking forward to what new things I bring to the table. We need some new leadership, better collaboration and better cooperation."
Earlier this year, Pugh said he would not seek re-election.
If Pugh steps down, only six council members will remain to conduct city business. Kwame Kenyatta resigned last week and City Council President Pro Tem Gary Brown moves July 1 to Orr's staff.
Detroit City Clerk Janice Winfrey said the council can continue to operate as long as there are enough members to make a quorum, but the loss of members will make it difficult for the smaller council committees to meet.
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Source: http://www.huffingtonpost.com/2013/06/27/charles-pugh-kevyn-orr-detroit-city-council_n_3507513.html
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Researchers find zinc's crucial pathway to the brain
June 26, 2013 ? A new study helps explain how parts of the brain maintain their delicate balance of zinc, an element required in minute but crucial doses, particularly during embryonic development.
The study, led at the Marine Biological Laboratory (MBL) by Mark Messerli in collaboration with scientists from the University of California, Davis, shows that neural cells require zinc uptake through a membrane transporter referred to as ZIP12.. If that route is closed, neuronal sprouting and growth are significantly impaired and is fatal for a developing embryo. Their discovery was published in the Proceedings of the National Academy of Sciences.
"This particular transporter is an essential doorway for many neurons in the central nervous system," explains Messerli. "You knock out this one gene, this one particular pathway for the uptake of zinc into these cells, and you essentially prevent neuronal outgrowth. That's lethal to the embryo."
Previously, scientists thought that zinc could use more than one pathway to enter the cell during early brain development. Some other elements, like calcium, enjoy such luxury of multiple options.
Knocking out ZIP12, affected several critical processes in the brain, the scientists found. For example, frog embryos were unable to develop their neural systems properly. Additionally, neurons had trouble reaching out to connect to other neurons; their extensions were both shorter and fewer in number than normal.
"We were surprised that ZIP12 was required at such an early and critical stage of development," said Winyoo Chowanadisai, a researcher in nutrition at the University of California at Davis and visiting scientist in the Cellular Dynamics Program at the MBL. Dr. Chowanadisai was the first on the team to realize that ZIP12 is expressed in such abundance in the brain."This study also reinforces the importance of periconceptional and prenatal nutrition and counseling to promote health during the earliest stages of life."
ZIP12 is part of a larger family of transporters involved in the movement of metal ions from outside the cell. Other reports showed that simultaneously blocking 3 other transporters in the family -- including ZIP1, 2, and 3 -- had no major effects on embryonic development.
Zinc is needed for healthy neural development, helping the brain to learn and remember new information. However, too much zinc can also be problematic.
The research team is investigating the implications of their results on processes like embryonic brain development and wound healing.
"[The result] was not expected," said Messerli, a physiologist in the MBL's Bell Center for Regenerative Biology and Tissue Enginering and Cellular Dynamics Program. ""We found that zinc uptake through ZIP12 is a regulatory point for neuronal growth, required for development and possibly required for learning and memory throughout life. We want to elucidate the downstream targets that zinc is affecting. That's the next exploration."
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Kerry plunges back into Mideast peace diplomacy
U.S. Secretary of State John Kerry, left, meets with Israeli Prime Minister Benjamin Netanyahu in Jerusalem on Thursday, June 27, 2013. Kerry is in Israel for the fifth time to make further efforts to resume peace talks between Israel and the Palestinians. (AP Photo/Jacquelyn Martin, Pool)
U.S. Secretary of State John Kerry, left, meets with Israeli Prime Minister Benjamin Netanyahu in Jerusalem on Thursday, June 27, 2013. Kerry is in Israel for the fifth time to make further efforts to resume peace talks between Israel and the Palestinians. (AP Photo/Jacquelyn Martin, Pool)
U.S. Secretary of State John Kerry meets with Israeli Prime Minister Benjamin Netanyahu, right, in Jerusalem on Thursday, June 27, 2013. Kerry is in Israel for the fifth time to make further efforts to resume peace talks between Israel and the Palestinians. (AP Photo/Jacquelyn Martin, Pool)
U.S. Secretary of State John Kerry, left, meets with Israeli Prime Minister Benjamin Netanyahu in Jerusalem on Thursday, June 27, 2013. Kerry is in Israel for the fifth time, to make further efforts to resume peace talks between Israel and the Palestinians. (AP Photo/Jacquelyn Martin, Pool)
U.S. Secretary of State John Kerry, left, shakes hands with Israeli Prime Minister Benjamin Netanyahu during their meeting in Jerusalem, on Thursday, June 27, 2013. Kerry is in Israel for the fifth time in three months, to make further efforts to resume peace talks between the Jewish country and the Palestinians. (AP Photo/Jacquelyn Martin, Pool)
U.S. Secretary of State John Kerry, left, shakes hands with Israeli Prime Minister Benjamin Netanyahu during their meeting in Jerusalem, on Thursday, June 27, 2013. Kerry is in Israel for the fifth time in three months, to make further efforts to resume peace talks between the Jewish country and the Palestinians. (AP Photo/Jacquelyn Martin, Pool)
AMMAN, Jordan (AP) ? Plunging back into the decades-long Israeli-Palestinian conflict, U.S. Secretary of State John Kerry held a four-hour meeting and fish dinner with Israeli Prime Minister Benjamin Netanyahu that stretched into the early hours of Friday.
It is Kerry's fifth visit to the region since becoming secretary of state in February to try to restart peace talks between the Israelis and Palestinians, which broke down in 2008. He is to have lunch with Palestinian President Mahmoud Abbas on Friday in Amman, and more meetings could be in the offing.
Kerry, who is on a two-week swing through the Mideast and Asia, left Amman on Thursday evening in a convoy of nearly a dozen vehicles for the roughly 90-minute drive to Jerusalem. A Jordanian military helicopter flew over his convoy during the trip, according to a reporter who was allowed to make the trip with Kerry and his delegation.
Netanyahu was about an hour late, apparently telling Kerry that he was delayed because he had been attending a graduation ceremony for Israeli military pilots. They talked mostly one-on-one, but advisers also were present for some of the discussion, which began around 9:30 p.m. local time in a suite at a hotel in Jerusalem and ended around 1:30 a.m. Friday.
The State Department released the dinner menu ? fish ceviche and a main course of red tuna and sea bream over lentils and mushrooms ? but offered no detailed information about their talks. The State Department said only that the two had a "productive, in-depth and wide-ranging conversation" and that Kerry reiterated his commitment to working with all parties to achieve a two-state solution.
There was no readout from the Israelis.
State Department officials say Kerry will continue to try to find common ground between the two sides that would lead to a re-launching of negotiations. On this trip, Kerry is trying to pin down precisely what conditions Abbas and Netanyahu have for resuming talks and perhaps discuss confidence-building measures.
Beyond that, Kerry wants to talk about the positive outcomes, such as enhanced economic growth, of a two-state solution. But at the same time, the secretary, who has long-time relationships with officials from both sides, will remind them of what's at stake if the conflict is left unresolved, they said.
Earlier this month, in a speech to the American Jewish Committee Global Forum in Washington, Kerry warned of serious consequences if no deal is reached.
"Think about what could happen next door," he told the Jewish audience. " The Palestinian Authority has committed itself to a policy of nonviolence. ... Up until recently, not one Israeli died from anything that happened from the West Bank until there was a settler killed about a month ago.
"But if that experiment is allowed to fail, ask yourselves: What will replace it? What will happen if the Palestinian economy implodes, if the Palestinian Security Forces dissolve, if the Palestinian Authority fails? ... The failure of the moderate Palestinian leadership could very well invite the rise of the very thing that we want to avoid: the same extremism in the West Bank that we have seen in Gaza or from southern Lebanon."
So far, there have been no public signals that the two sides are narrowing their differences.
Abbas has said he won't negotiate unless Israel stops building settlements on war-won lands or accepts its 1967 lines ? before the capture of the West Bank, Gaza Strip and east Jerusalem in a Mideast war that year ? as a starting point for border talks. The Palestinians claim all three areas for their future state.
Netanyahu has rejected the Palestinian demands, saying there should be no pre-conditions ? though his predecessor conducted talks on the basis of the pre-1967 lines, and the international community views the settlements as illegal or illegitimate.
Earlier on Thursday, Kerry talked about the crisis in Syria and the Mideast peace process over lunch with Jordan's King Abdullah II.
In a statement, the Royal Palace said Abdullah told Kerry that he will continue trying to bridge the gaps in the viewpoints of Palestinians and Israelis. But he warned that Israel's "unilateral actions, which include continuous Israeli trespassing on Christian and Muslim holy sites, undermine chances for peace."
On Wednesday, an Israeli planning committee gave the final approval for construction of dozens of new homes in a settlement in east Jerusalem. The announcement, which was made the day before Kerry's visit, appeared to be an Israeli snub at the secretary of state's latest round of Mideast diplomacy.
Officials traveling with Kerry sought to minimize the significance of the announcement, saying the U.S. has repeatedly said that continued construction of settlements were unhelpful to efforts to restart the talks. The settlements are part of the Har Homa area of east Jerusalem. The Obama administration said it was "deeply concerned" back in 2011 when an Israeli planning commission approved 930 new housing units in the Har Homa neighborhood.
The Palestinian side condemned the announcement.
"Such behavior proves that the Israeli government is determined to undermine Secretary Kerry's efforts at every level," said Palestinian negotiator Saeb Erekat.
___
Associated Press writer Jamal Halaby in Amman contributed to this report.
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Gene deletion affects early language and brain white matter
June 27, 2013 ? A chromosomal deletion is associated with changes in the brain's white matter and delayed language acquisition in youngsters from Southeast Asia or with ancestral connections to the region, said an international consortium led by researchers at Baylor College of Medicine. However, many such children who can be described as late-talkers may overcome early speech and language difficulties as they grow.
The finding involved both cutting edge technology and two physicians with an eye for unusual clinical findings. Dr. Seema R. Lalani, a physician-scientist at BCM and Dr. Jill V. Hunter, professor of radiology at BCM and Texas Children's Hospital, worked together to identify this genetic change responsible for expressive language delay and brain changes in children, predominantly from Southeast Asia.
Lalani, assistant professor of molecular and human genetics at BCM, is a clinical geneticist and also signs out diagnostic studies called chromosomal microarray analysis, a gene chip that helps identify abnormalities in specific genes and chromosomes, as part of her work at BCM's Medical Genetics Laboratory.
"I got intrigued when I kept seeing this small (genomic) change in children from a large sample of more than 15,000 children referred for chromosomal microarray analysis at Baylor College of Medicine. These children were predominantly Burmese refugees or of Vietnamese ancestry living in the United States. It started with two children whom I evaluated at Texas Children's Hospital and soon realized that there was a pattern of early language delay and brain imaging abnormalities in these individuals carrying this deletion from this part of the world. Within a period of two to three years, we found 13 more families with similar problems, having the same genetic change. There were some children who obviously were more affected than the others and had cognitive and neurological problems, but many of them were identified as late-talkers who had better non-verbal skills compared to verbal performance," said Lalani. Hunter, helped in determining the specific pattern of white matter abnormalities in the MRI (magnetic resonance imaging) scans in children and their parents carrying this deletion. Most of the children either came from Southeast Asia or were the offspring of people from that area. (White matter is the paler material in the brain that consists of nerve fibers covered with myelin sheaths.)
Now, in a report that appears online in the American Journal of Human Genetics, Lalani, Hunter and an international group of collaborators identify a genomic deletion on chromosome 2 that is associated with bright white spots that show up in an MRI in the white matter of the brain . The chromosomal deletion removes a portion of a gene known as TM4SF20 that encodes a protein that spans the cellular membrane. They do not know yet what the function of the protein is. They found this genetic change in children from 15 unrelated families mainly from Southeast Asia.
"This deletion could be responsible for early childhood language delay in a large number of children from this part of the world," says Lalani.
She credits Dr. Wojciech Wiszniewski, an assistant professor of molecular and human genetics at BCM with doing much of the work. Wiszniewski has an interest in genomic disorders and is working under the mentorship of Dr. James R. Lupski, vice chair of the department of molecular and human genetics.
Lupski said, "Professor Lalani has made a stunning discovery in that she provides evidence that population-specific intragenic CNV (copy number variation -- a deletion or duplication of the chromosome) can contribute to genetic susceptibility of even common complex disease such as speech delay in children."
"In a way, this is a good news story," said Hunter. There is evidence from family studies that some of these children may do quite well in the future, said Lalani.
Lalani elaborates. "This is a genetic change that is present in 2 percent of Vietnamese Kinh population (an ethnic group that makes up 90 percent of the population in that country)," she said. "In the 15 families we have identified, all children have early language delay. Some are diagnosed with autism spectrum disorder, and if you do a brain MRI study, you find white matter changes in about 70 percent of them. We have found this change in children who are Vietnamese, Burmese, Thai, Indonesian, Filipino and and Micronesian. It is very likely that children from other Southeast Asian countries within this geographical distribution also carry this genetic change."
Because these are all within a geographic location, she suspects that there is an ancient founder effect, meaning that at some point in the distant past, the gene deletion occurred spontaneously in an individual, who then passed it on to his or her children and to succeeding generations.
"It is important to follow these children longitudinally to see how these late-talkers develop as they grow," said Lalani. "We have also seen this deletion in children whose parents clearly were late-talkers themselves, but overcame the earlier problems to become doctors and professionals. The variability within the deletion carriers is fascinating and brings into question genetic and environmental modifiers that contribute to the extent of disease in these children.
Language delays mean that they may speak only two or three words at age 2, in comparison to other children who would generally have between 75-100 word vocabulary by this age. While there is evidence that children with this deletion may catch up, it is unclear if they continue to have better non-verbal skills than verbal skills. It is also unclear how the specific brain changes correlate with communication disorders in these children.
In fact, when doctors check the parents of these children, they often find similar white matter changes in the parent carrying the deletion. "Young parents in their 30s should not have age-related white matter changes in the brain and these changes should definitely not be present in healthy children," said Lalani. Hunter said they are not sure how the gene variation relates to the changes in brain white matter and how all of these result in delay in language.
Others who took part in this work include Neil A. Hanchard, Chad Shaw, Qi Tian, Anna Illner, Xueqing Wang, Sau W. Cheung, Ankita Patel, Ian Campbell, Patricia Hixson, Audrey R. Ester, Mahshid S. Azamian, Lorraine Potocki, Gladys Zapata, Patricia P. Hernandez, Melissa B. Ramocki, Regie L.P. Santos-Cortez, Gao Wang, Michele K. York, Monica Justice, Zili D. Chu, Heather P. Crawford, Carlos A. Bacino, Adiaha I.A. Franklin, Robin Goin-Kochel, Pawel Stankiewicz, Arthur L. Beaudet, Mirjana Maletic-Savatic, John W. Belmont, Suzanne M. Leal, Muhammad E. Haque, Marija Stosic, and Penelope Bonnen ; all of BCM; Jason R. Willer, Erica E. Davis, and Nicholas Katsanis, all of Duke University Medical Center in Duham, North Carolina; Nirupama S. Madduri, Misti D. Williams, Thomas M. Morgan, Sumit Pruthi and Reed Omary of Vanderbilt University in Nashville, Tennesee; Gunter Scharer of Children's Hospital in Aurora, Colorado, Pattamawadee Yanatatsaneejit and Apiwat Mutirangua of Chulalongkorn University in Bangkok, Thailand; Anna Eifert of the Department of Speech and Language at Texas Children's Hospital; Jeffery Kerr, Gayle Simpson and Ladonna Immken of Dell Children's Medical Center in Austin, Texas; Patricia I. Bader and Lisa Omo-Griffith of Northeast Indiana Genetic Counseling Center in Fort Wayne; Simeon A. Boyadjiev of University of California Davis; Kay K. Win Harlem Hospital Center in New York; Aye Thida of Allcare Pediatrics in Missouri City, Texas; Matthew Hurlesof Wellcome Trust Sanger Institutue in Cambridge, United Kingdom; Martin Lloyd Hibberd and Chiea Chuen Khor of Genome Institute of Singapore; Nguyen Van Vinh Chau, Sarah Dunstan and Cameron Simmons of the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam, Thomas E. Gallagher of Tripler Army Medical Center in Honolulu, Hawaii; Jill A. Rosenfeld of Signature Genomic Laboratories of PerkinElmer, Inc. in Spokane, Washington and Lisa G. Shaffer of Paw Print Genetics in Spokane, Washington.
Funding for this work came from the Doris Duke Charitable Foundation and Gillson Longenbaugh Foundation, the National Institutes of Health (RO1-HL091771) and National Institute of Neurological Disorders and Stroke (RO1-NS058529-03, Career Development Award K23NS078056 ( Wiszniewski) and 5K08NS062711), the National Human Genome Research Institute (5U54HG006542), the Molecular Medicine Scholars Program at BCM (HL-66991), the McKnight Endowment for Science, Dana Foundation, and the NIH Intellectual and the Developmental Disabilities Research Grant (P30HD024064), the Children's Medical Network endowed chair in pediatric genetics.
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Calcium and vitamin D help hormones help bones
June 26, 2013 ? Should women take calcium and vitamin D supplements after menopause for bone health? Recommendations conflict, and opinions are strong. But now, an analysis from the major Women's Health Initiative (WHI) trial throws weight on the supplement side -- at least for women taking hormones after menopause. The analysis was published online today in Menopause, the journal of The North American Menopause Society.
Among the nearly 30,000 postmenopausal women in the hormone trial, some 8,000 took supplemental calcium (1,000 mg/day) and vitamin D (400 mg/day), and some 8,000 took look-alike placebos. These women came from all the hormone groups in the study -- those who took estrogen plus a progestogen (required for women with a uterus), those who took estrogen alone, and those who took the hormone look-alike placebos. The researchers looked at how the rates of hip fracture differed among women who took hormones and supplements, those who took hormones alone, and those who took neither.
The supplements and hormones had a synergistic effect. Women using both therapies had much greater protection against hip fractures than with either therapy alone. Taking supplements alone wasn't significantly better than taking no supplements and no hormones. The benefit of hormone therapy was strong in women who had a total calcium intake (supplements plus diet) greater than 1,200 mg/day. Similarly, the benefit was strong in women who had higher intakes of vitamin D, but the individual effect of each one could not be determined because the two supplements were given together.
The effects translated into 11 hip fractures per 10,000 women per year among the women who took both hormones and supplements compared with 18 per 10,000 women per year among those who took hormones only, 25 per 10,000 women per year among those who took supplements alone, and 22 among those who got neither therapy.
These results suggest, said the authors, that women taking postmenopausal hormone therapy should also take supplemental calcium and vitamin D. Although they couldn't specify how much, they noted that the benefits seem to increase with increasing total intake of calcium and vitamin D. The dose will depend on keeping side effects, such as constipation from too much calcium, to a minimum, they said.
That differs from the recommendation of the US Preventive Services Task Force (USPSTF), made earlier this year. USPSTF stated there was no basis for recommending calcium and vitamin D supplements to prevent fractures. But now, with a study this large, there may well be.
The study will be published in the February 2014 print edition of Menopause.
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Thursday, June 27, 2013
Recon Jet HUD now available for pre-order in $499 Pilot Edition
Want to embrace Recon Instruments' sunglasses-based vision of the future before it officially reaches store shelves? You can: the company has just started pre-orders for its Jet heads-up display in a $499 Pilot Edition. The inaugural eyewear will come with apps for both cyclists and triathletes, and it should beat the production model to market by several months. There's even a financial incentive for that impatience, as the pricing goes up to $599 on July 21st. If you don't mind a potentially rough experience while tracking your mid-race performance, the Pilot Edition is waiting at the source link.
Filed under: Displays, Wearables
Source: Recon Instruments
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/dgeMBELj1PE/
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Behold the First Images of the Official Lego Back to the Future Set!
Brick News has obtained photos of the official Lego Back to the Future set, including the minifigs for Marty McFly and Doc Brown. As you can see, it's more elaborated than the version approved by Lego Cuusoo
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